If you’re ready to build serious muscle without spending every day in the gym, a well-structured 4-day hypertrophy split is one of the most efficient ways to get there. Designed to maximize muscle growth through volume, intensity, and smart recovery, this type of routine is ideal for intermediate to advanced lifters aiming to pack on size and strength — even with a busy schedule.
Why a 4-Day Hypertrophy Split Works
A hypertrophy-focused training split is built around the science of muscle growth: progressive overload, sufficient volume per muscle group, and optimal recovery time. Spreading your workouts over four days allows each muscle group to get targeted attention while ensuring enough rest between sessions to grow.
Compared to full-body or 3-day routines, a 4-day split for hypertrophy offers:
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Greater training volume per session
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Enhanced muscle focus and mind-muscle connection
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More time to recover without sacrificing frequency
Best 4-Day Split for Hypertrophy
There’s no one-size-fits-all routine, but some structures stand out for effectiveness. Here's a classic approach that balances upper and lower body training across the week:
Day 1 – Upper Body Push (Chest, Shoulders, Triceps)
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Bench Press – 4 sets x 8-12 reps
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Dumbbell Shoulder Press – 3 sets x 10-12 reps
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Incline Dumbbell Press – 3 sets x 8-10 reps
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Cable Lateral Raise – 3 sets x 12-15 reps
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Overhead Triceps Extension – 3 sets x 10-12 reps
Day 2 – Lower Body (Quads, Glutes, Calves)
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Barbell Back Squat – 4 sets x 8-10 reps
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Walking Lunges – 3 sets x 12 steps per leg
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Leg Press – 3 sets x 10-12 reps
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Glute Bridges – 3 sets x 12-15 reps
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Seated Calf Raise – 3 sets x 15-20 reps
Day 3 – Upper Body Pull (Back, Biceps)
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Pull-Ups – 4 sets to failure
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Barbell Row – 3 sets x 8-10 reps
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Lat Pulldown – 3 sets x 10-12 reps
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Dumbbell Curl – 3 sets x 10-12 reps
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Face Pulls – 3 sets x 15 reps
Day 4 – Posterior Chain + Arms Focus
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Romanian Deadlift – 4 sets x 8 reps
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Hamstring Curl – 3 sets x 12 reps
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Rear Delt Fly – 3 sets x 12-15 reps
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Cable Rope Hammer Curl – 3 sets x 12 reps
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Triceps Pushdown – 3 sets x 12-15 reps
Key Principles for Hypertrophy Success
A 4 day workout split hypertrophy program isn’t just about the exercises — it’s about execution. Keep these principles in mind to get the most out of your routine:
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Progressive Overload: Gradually increase weights or reps weekly.
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Recovery: Take rest days seriously. Muscles grow when you rest, not during the workout.
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Nutrition: Fuel with a high-protein diet and enough calories to support growth.
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Form First: Prioritize proper technique over heavier loads.
Who Should Use a 4-Day Hypertrophy Program?
This setup is ideal if you:
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Have 4 consistent days a week to train
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Want to balance size gains with lifestyle flexibility
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Are past the beginner stage and need more volume per muscle group
Whether you’re training for aesthetics, performance, or both, this hypertrophy 4-day split delivers efficient gains without the burnout of daily training.
Final Thoughts
If you're looking for the best 4 day split for hypertrophy, it comes down to consistency, intensity, and a plan tailored to your body and goals. Stick with it, track your progress, and your results will speak for themselves.
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